Oestrogen Balance Report

Oestrogen is one of the two major female steroidal sex hormones, the other being progesterone. Men also require oestrogen for producing sperm and maintaining libido, but at significantly lower levels. Oestrogen main role is to increase the growth and production of cells. It is responsible for the development of the female reproductive system and is also involved in maintaining bone density, blood clotting and affects hair, skin, mucous membranes and pelvic muscles.

Oestrogen imbalance can contribute to female gynaecological issues including fibroids, PMS, and heavy menstrual bleeding, skin-related issues including acne and rashes, and ER positive breast cancer.

The Oestrogen Balance test analyses genes involved in the oestrogen lifecycle. It looks at how gene variants affects production, activation and elimination of oestrogens as well as detailing the nutrients and environmental factors that can influence and improve their balance. The Oestrogen Balance report is recommended for women who suspect oestrogen-linked conditions.

Genes Included

Synthesis: CYP17A1, CYP19A1 and SULT2A1
Activation: CYP1A1, CYP1B1 and CYP3A4
Receptors: ESR1 and ESR2
Methylation: COMT and MTHFR
Metabolism: GSTM1, GSTP1, SULT1A1, SULT1E1 and UGT1A1

All of the Lifecode Gx reports include

  • personalised, colour coded genotype results

  • gene function and SNP impact descriptions

  • clinically relevant SNPs

  • nutrient and other epigenetic impacts

  • links to research evidence